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2009, discovery of a different phenotype for germs in slim nanofluidic slits; and 1st detection of community protein buildings together DNA applying solid-point out nanopores

Our group experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells that will autonomously divide. Our major curiosity lies in cell division, chromatin composition, and spatial Management.

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I'm able to barely envision how I, as being a geneticist, would be capable to discover elementary physics, let alone contend at the best. How did you go about it?

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style in 2005. (nl)

SMC complexes can move physical roadblocks bigger than their ring sizing, indicating a nontopological system for DNA loop extrusion

Size control of unique carbon nanotubes by nanostructuring Together with the scanning tunneling microscope

Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation

‘Yes, I understand men and women were stunned at some time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t study A lot anymore. The sphere went much more into the appliance facet, how you may combine nanotubes into Digital circuits.

Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding because the step-generating procedure

An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes

1999, initial measurement from the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for just a new Luttinger description of interacting electrons in nanotubes

For instance, we think about the nucleopore advanced, a gateway amongst the cell nucleus and the cytoplasm. This is a really challenging program and therefore tricky to review within a mobile, so we use biomimetics. We reconstruct holes and afterwards insert personal aspects on the nucleopore complicated https://www.ceesdekker.net to check transport through it at The only-molecule level.’

It had been an exceptionally fascinating time, for the duration of which I been given lots of help from Delft College of Technological know-how, exactly where I used to be a professor at enough time, And that i started off several collaborations with molecular biologists. That helped me find out quite a bit.’